Supraclavicular lymphadenopathy. Lymphadenopathy of the lymph nodes - a sign of a serious illness or simple inflammation? What does enlargement and inflammation of the lymph nodes mean?

Lymphatic system - an integral part of the vascular system, which has several functions. It takes part in metabolic processes, cleansing the body of foreign particles, neutralizing pathogenic microorganisms, etc.

One of the constituent elements of the lymphatic system are the lymph nodes. For certain health problems cervical lymph nodes begin to increase, that is, lymphadenopathy develops.

What is lymphadenopathy?

Lymphadenopathy is a condition in which the lymph nodes are under the influence of certain factors. Lymph nodes are a structural unit of immunity that performs filter function in the lymphatic system.

And macrophages, which are located in the lymph nodes, kill the microorganisms that have entered the system, absorb dead cells, coarse proteins.

When foreign cells enter the nodes, lymphoid tissues begin to produce antibodies, and grow accordingly.

Node enlargement in diameter more than 1 cm is considered a pathology.

Lymphadenopathy can be a short-term response to an infectious process, or be a symptom of a number of pathologies that are different in nature, clinical signs, and treatment methods. Any pathological conditions can cause the growth of lymphoid tissues.

Lymphadenopathy can appear in several areas of the body or localized in one place. Cervical lymphadenopathy can occur in isolation, or be part of a generalized process.

Difference from lymphadenitis

When an infection enters the lymph nodes, their protective function may not work, and then inflammation, lymphadenitis develops. And lymphadenopathy (hyperplasia of the nodes) can be a syndrome of this inflammation.

The infection can enter the node through open wounds or enter with the lymph flow. Often, lymphadenitis is accompanied by suppuration, which requires surgical intervention.

Lymph nodes with lymphadenitis are always painful. Lymphadenopathy can be painless.

For cancers lymph nodes trap malignant cells where they settle. They begin to divide and grow metastases. The nodes increase, and the inflammatory process, as a rule, is not observed.

Watch a video about the causes of swollen lymph nodes:

Types of disease

The cervical lymph nodes are divided into several groups:

  1. Anterior: superficial and deep;
  2. Lateral: superficial and deep.

Depending on where and how deep they are located, they filtration of lymph from different parts of the body(oral cavity, thyroid gland, etc.).

When an isolated disease of one of these organs develops local lymphadenopathy. With systemic lesions, the syndrome may appear generalized hyperplasia of the nodes.

According to the prevalence of lymphadenopathy of the neck is:

  1. local (1 lymph node is enlarged);
  2. regional (increase in nodes of 1 or 2 adjacent groups);
  3. generalized (more than 3 groups).

Forms by the nature of the flow:

  1. acute;
  2. chronic;
  3. recurrent.

Reasons for the appearance

Growth of nodes in adults and children may be associated with infectious and non-infectious factors. In 95% of cases, the syndrome has an infectious origin.

infectious causes:

Lymphadenopathy of the cervical nodes is more often associated with oral infections. It usually occurs in young children and adolescents with childhood infections. This is due to the immaturity of the children's immune system, which may not always adequately respond to various stimuli.

If you remove the root cause of the syndrome, it can go away on its own.

Most at risk for developing lymphadenopathy unvaccinated children against rubella, measles, mumps, diphtheria. These diseases are usually accompanied by an increase in the anterior cervical lymph nodes.

About 5% of cases are associated with non-infectious factors. Lymphadenopathy can be a symptom of oncological processes:

  • leukemia;
  • neuroblastoma.

One of the causes of hyperplasia may be a nonspecific infection. This is a pathology that provokes conditionally pathogenic microflora, permanently residing in our body.

If a person is healthy, she is in a calm state, without causing any problems. But when beneficial conditions are created (nervous strain, illness, injury), conditionally pathogenic organisms begin to develop intensively, which leads to the development of diseases.

Symptoms

The main symptom of lymphadenopathy of the cervical lymph nodes is the presence of nodules. They can have different characteristics, depending on the pathology that caused the lymphadenopathy. Healthy nodes should not exceed 1-1.5 cm in diameter.

If the enlargement of the nodes is accompanied by pain, this sign of inflammation. In this case, abscesses can form, the skin acquires a bright red tint. With an infectious-inflammatory nature of the lesion, the nodes are soft, elastic.

Compaction may be evidence of metastasis.

In addition to an increase in nodes, lymphadenopathy may be accompanied by:

  1. sudden unreasonable weight loss;
  2. increased sweating;
  3. rash;
  4. liver enlargement.

Diagnostics

First, the physician must careful examination of the affected area, determine the size of formations, their consistency, localization. It is necessary to take an anamnesis in order to determine, if possible, the conditions that could trigger the development of lymphadenopathy.

Since this syndrome can accompany many diseases, it is necessary to a number of laboratory and instrumental studies to determine them:

  • detailed blood test;
  • analysis for hepatitis and HIV;
  • Ultrasound of the abdominal organs and enlarged lymph nodes;
  • histology and biopsy of the node;
  • MRI, CT, radiography.

Treatment

Full treatment can be prescribed only if if the exact cause of the enlarged lymph nodes is known and a diagnosis is made.

The first thing to do - eliminate root cause:

In most cases, lymphadenopathy may resolve on its own within 4-6 weeks if the underlying cause is corrected.

If after this time there are no signs of a decrease in the lymph nodes, these are indications for a biopsy.

The tuberculous etiology of the syndrome requires a course of taking anti-tuberculosis drugs in a hospital setting (Isoniazid, Ethambutol, etc.).

If lymphadenopathy is accompanied by pain, symptomatic treatment with analgesics. The presence of purulent formations is an indication for surgical opening and drainage.

In children, under certain circumstances, the cervical lymph nodes may remain slightly enlarged for a long time. In this case, you just need to watch them.

If there is a constant increase in nodes, despite the therapeutic measures taken, it is necessary to sound the alarm and urgently consult a doctor.

Prevention

Unfortunately, there are no special preventive measures that can protect against lymphadenopathy. Swollen lymph nodes can be a sign of various diseases. And it is impossible to protect yourself from all at once.

Lymphadenopathy is a signal that the body pathological processes take place. This can be a symptom of both a simple SARS and more serious ailments, including malignant tumors.

That's why the appearance of seals, "bumps" in the area of ​​​​lymph nodes should be the reason for an immediate visit to the doctor, and a thorough examination of the body.

Lymphadenopathy - what it is can be found out after examination by the attending physician. The disease is caused by an increase in lymph nodes in size. Hyperplasia is directly related to lymphadenopathy, since this is the growth and reproduction of tissues, which can lead to the appearance of swelling and swelling in any part of the body.

Such pathologies often indicate the possible development of an oncological process in a patient. In order to diagnose the disease, several different tests, laboratory tests, and instrumental diagnostics are used. The disease is very dangerous, as it can affect the internal organs of a person.

Reasons for the development of the disease

The factors that influence the development of lymphadenopathy (and as a special case of hyperplasia) are different. To provoke an increase in lymphatic (especially regional) nodes can:

  1. Various viral infections.
  2. Infection of the lymph nodes themselves.
  3. Connective tissue disease or injury. Exposure to various medications, such as serum.
  4. Infectious lesions that greatly reduce the level of immunity in the patient.
  5. fungal infection.

Unlike adults, lymphadenopathy (or hyperplasia) on nodules in children develops in the abdominal cavity.

This is due to the fact that a child from birth is attacked by bacteria and viruses through their introduction into the gastrointestinal tract. With such a lesion, the baby should be taken to the doctor.

Hyperplasia of the lymph nodes often occurs with chickenpox, HIV, tuberculosis, rubella. It can appear with scratches from the claws of the animal. Most often it is seen in the neck, armpits, under the jaw. The disease can also develop during a sexually transmitted disease, for example, with syphilis. Tuberculosis affects the chest and mediastinum.

Symptoms of the described disease

Symptoms of the disease depend on the cause of the development of pathology. Most often observed:

  1. Various rashes on the skin.
  2. Increase in body temperature.
  3. Excessive perspiration (particularly at night).
  4. Fever attacks are possible.
  5. A person abruptly loses body weight, although there are no apparent reasons.

Hyperplasia of the lymph nodes can be painful, especially if their size increases by more than 2 cm. When probing, you can see that the consistency of the nodule is elastic and soft. This usually occurs with an infection or inflammatory process, when the nodes rapidly increase in size. If growth occurs slowly, then they are denser, they do not give pain. Most often, this process occurs with oncological lesions.

If there is an increase in nodules on the neck or under the jaw, then usually the hyperplasia of the lymph nodes is benign. In the event that such a process occurs in the supraclavicular region, abdominal cavity, mediastinum, then the tumor will be malignant.

How is lymphadenopathy classified?

The disease can be generalized, localized or reactive.. The first form of the disease is the most dangerous, as it immediately covers a large number of lymph nodes. The local type of lesion affects only 1 group of lymph nodes.

The generalized form of the disease can be allergic, autoimmune, acute, inflammatory or infectious in nature, which can affect the internal organs of the patient. Most often it develops on the neck, underarms and in the area behind the peritoneum. Sometimes it occurs in the groin and supraclavicular area.

The reactive type of lymphadenopathy is caused by the reaction of the patient's body to an infectious lesion. It can develop in all lymph nodes. There are no obvious symptoms with him, there is no pain.

Lymphadenopathy is divided into acute, chronic and recurrent form..

It can pass in the form of a tumor and without it, but is life-threatening for the patient.

The mediastinum, armpits, neck, lungs, groin, submandibular zone, mammary glands suffer.

Hyperplasia of the lymph node occurs with hyperthyroidism, the use of serum, a deficiency of B vitamins.

Lymphadenopathy of various organs

An increase in the size of the lymph nodes in the peritoneum is caused by infection or inflammation. Sometimes this happens due to the development of a cancerous tumor or impaired immunity. Children may have a fever at night with this disease. General weakness, nausea and severe malaise appear.

If the mammary glands are affected, then doctors often detect an oncological disease, and sometimes a cancerous tumor. Therefore, you need to urgently seek help from a doctor. If the nodules have increased in the upper zone of the glands, then the tumor is usually benign - but it can be transformed into a malignant form. If this happened in the lower part of the mammary gland, then a cancerous lesion has arisen. Although the patient does not feel any pain, it is urgent to go to the doctor.

With the growth of lymph nodes in the mediastinum (this is the anatomical region in the chest area), large vessels will be affected due to the defects on them. This occurs with a viral or infectious lesion.

Lymphadenopathy in this case passes with severe pain in the chest, which then passes to the neck and shoulders. The patient's pupils dilate or the eyeball sinks. If the process is chronic, then the patient has hoarseness. The head may hurt, food is difficult to pass to the stomach. Patients complain of a noise in the head, some of them turn blue in the face, and veins swell in the neck. The temperature may rise, swelling of the arms and legs may begin, weakness occurs, and the rhythm of the heart is disturbed. If a child is sick, then he may have trouble breathing, sweating a lot at night. In such cases, the child must be hospitalized.

Other types of illness

Hyperplasia of the lymph nodes may appear on the lungs. At the same time, in the worst case, the disease can be caused by a tumor with metastases. Usually the process is bilateral, when the mediastinum or cervical region is affected along with the lung. Symptoms of an increase in nodules on the lungs are as follows: severe pain during swallowing, cough, fever, soreness in the chest. Signs of such a lesion are manifested in tuberculosis, injuries. Alcoholism or smoking can lead to this situation.

Lymphadenopathy in the submandibular region occurs in adolescents and preschool children. But such ailments are temporary. They do not threaten the life of the child. Often the cause of the disease is an oncological lesion, so these children should be urgently taken for examination.

The disease can develop under the armpits even from an ordinary hand injury or when an infectious lesion occurs. Inflammation in the lymphatic nodules of the armpits is also possible with damage to the mammary glands. With timely detection of the disease, the person recovers completely.

Diagnosis and treatment of lymphadenopathy

Diagnosis is based on tests with cancer markers. Ultrasound is used to examine the abdominal cavity, radiography. General blood and urine tests, tests for syphilis and HIV, biopsy and other laboratory and instrumental tests are done.

Self-medication for such diseases does not help, so it is better not to do it, as this can lead to disastrous results.

If the enlargement of the lymph nodes was due to infection or the development of an inflammatory process, then antibiotics are used that eliminate pathogenic microorganisms. If the disease appeared due to staphylococci, then penicillin cannot be used, since these viruses are resistant to it. Therefore, doctors select the right medication from other groups of antibiotics, for example, tetracycline, etc.

If the disease has arisen due to tuberculosis, syphilis or another specific ailment, then special treatment methods are used to eliminate it.

If the growth of lymph nodes in a patient has led to a sharp increase in the amount of connective tissue, and there is a tumor process, then doctors use a surgical operation.

Disease prevention

Lymph nodes are small formations that are the main component of the peripheral immune system. They act as a physical barrier to microbes, antigens and other particles from the tissues of the skin, gastrointestinal tract, bronchi, filtering them from the interstitial fluid that flows into the node from the periphery. The size of a lymph node depends on the age of the person, the location of the node in the body, and previous immunological events. Normally, the size of the node ranges from a few millimeters to 1 cm.

Lymph nodes are located in groups of several pieces throughout the human body; out of more than 500 nodes in healthy people, only those located in the neck, armpits, and groin can be palpated. Under the influence of several factors, the lymph nodes change their size and consistency.

Symptoms and types of disease

This condition is characterized by the following symptoms:

  • the presence of a painful, warm, reddened swelling under the skin, sometimes purulent inflammation can be observed;
  • skin rashes;
  • unexplained weight loss;
  • fast fatiguability;
  • and the liver (organs that filter the blood);
  • fever, night sweats.

Based on the prevalence of enlarged lymph nodes, the following types of disease are distinguished:

  • localized (one lymph node is enlarged in one area);
  • regional (several lymph nodes are enlarged in one or two adjacent areas);
  • generalized (lymph nodes are enlarged in two or more non-adjacent areas)

This classification is important in the differential diagnosis. According to medical statistics, approximately three quarters of patients with unspecified lymphadenopathy have localized and regional forms and one quarter of patients have a generalized form.

Reactive lymphadenopathy develops in response to infectious inflammation, allergies, or an autoimmune disease. Illness in young children most often submandibular and cervical) is the most common, as their immune systems are just beginning to respond to the infections they have encountered. Lymphadenopathy occurs in 1/3 of newborns and infants and rarely has a generalized form ( only in the presence of a congenital infection, such as cytomegalovirus).

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The reasons

Lymphadenopathy is usually caused by a bacterial (syphilis, tuberculosis, plague, etc.) or viral infection (HIV, infectious mononucleosis, cytomegalovirus, chickenpox, adenovirus). When a lymph node is infiltrated with inflammatory cells, it becomes infected (lymphadenitis). Other causes of the pathological condition include:

  • drug or vaccine allergies (eg, reaction to phenytoin, allopurinol, immunization);
  • cancer (leukemia, acute lymphoblastic leukemia, lymphoma, etc.);
  • diseases that affect tissues that support, connect, and protect organs;
  • storage diseases (Niemann-Pick disease, Gaucher disease);
  • autoimmune diseases (juvenile rheumatoid arthritis, sarcoidosis).

Characteristic location of affected lymph nodes

Lymphadenopathy of the submandibular nodes develops with diseases of the teeth, tongue, gums, oral mucosa, is the result of a local infection, such as pharyngitis, gingivitis, stomatitis, or jaw abscess. Children are diagnosed more often than other localizations.

Cervical lymphadenopathy is also a common problem in children and is often associated with an infectious etiology. Inflammation or direct infection of the tissues of the tongue, external ear, parotid gland, larynx, thyroid gland or trachea causes hyperplasia of the corresponding group of nodes. It develops with viral infections of the upper respiratory tract, streptococcal pharyngitis, acute bacterial lymphadenitis. In some cases, the pathology of this localization may be of a non-infectious nature (with neuroblastoma, leukemia, Hodgkin's lymphoma, Kawasaki disease).

Common causes of axillary lymphadenopathy are local infectious lesions, cat-scratch disease. Axillary lymphadenopathy can develop after vaccination in the arm, with brucellosis, juvenile rheumatoid arthritis and non-Hodgkin's lymphoma.

Mediastinal is observed in diseases of the chest organs (lungs, heart, thymus and esophagus). An increase in supraclavicular lymph nodes is often associated with mediastinal lymphadenopathy and indicates malignant diseases of the breast and lungs. Unlike other localizations, mediastinal lymphadenopathy rarely occurs as a result of infection (may develop with tuberculosis, histoplasmosis, coccidioidomycosis), and is usually a sign of a serious underlying disease. Lymphomas and acute lymphoblastic leukemia are the causes of damage to the anterior mediastinum.

Intrathoracic occurs with such systemic lung diseases as sarcoidosis, cystic fibrosis, as well as with malignant tumors of the chest organs and with metastasis of tumors of other organs. Intrathoracic can cause cough, wheezing, dysphagia, airway erosion with hemoptysis, atelectasis, and obstruction of large blood vessels (superior vena cava syndrome) – a medical emergency.

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Retroperitoneal lymphadenopathy is indicative of lymphoma or other cancer.

Pain in the abdomen, back, increased frequency of urination, constipation and intestinal obstruction may be signs of abdominal lymphadenopathy, which is observed in acute mesenteric adenitis (mesadenitis) and lymphoma. Mesadenitis is considered a disease of viral etiology, which is characterized by abdominal pain in the right lower quadrant, caused by an increase in lymph nodes near the ileocecal valve. Mesenteric occurs in non-Hodgkin's lymphoma, Hodgkin's lymphoma, typhoid fever, ulcerative colitis.

Tissue fluid from the lower extremities, perineum, buttocks, genitals, and lower abdomen flows through the inguinal and pelvic lymph nodes. Inguinal lymphadenopathy can be caused by infection, syphilis, venereal lymphogranulomatosis, insect bites, in children - diaper dermatitis.

Differential Diagnosis

Careful study of the patient's medical history, proper physical examination, assessment of the size, location, and nature of the enlarged lymph nodes, along with any associated clinical findings, are important in making the differential diagnosis. To identify the cause of the disease, the following studies may be required:

  • laboratory blood tests may show the presence of an infection or other medical condition;
  • chest x-ray can be informative for detecting pathologies such as mediastinal and associated major lung diseases, including tuberculosis, lymphoma, neuroblastoma, pulmonary coccidioidomycosis, histiocytosis, Gaucher disease, etc.;
  • ultrasound is used to characterize any changes in the lymph nodes and the degree of involvement of the lymph nodes in the inflammatory process. But in children, ultrasound rarely has diagnostic value, since lymph nodes less than 1 cm in size are poorly visualized;
  • computed tomography of the chest and abdomen with or without intravenous contrast. It is used in the detection of lesions of the supraclavicular lymph nodes, which is associated with a high risk of malignant disease;
  • magnetic resonance imaging (MRI) can be used to differentiate malignant mediastinal lymphadenopathy in children from benign;
  • biopsy of a pathologically altered lymph node. It is necessary if the prevalence, location and nature of lymphadenopathy indicates a malignant process. If the biopsy does not reveal the diagnosis, a repeat procedure may be indicated.

Lymphadenopathy is a fascination with the size of the lymph nodes of the most diverse localization. In most cases, this condition is only a manifestation of the underlying disease. In the absence of the necessary assistance, an uncontrolled increase in lymph nodes can lead to serious complications that threaten the health and even life of the patient.

Why are lymph nodes needed?

So, lymphadenopathy. What is it and how to deal with it? Before asking a similar question, you should understand what function the lymph performs. This colorless liquid penetrates all organs, returning all the nutrients from the tissues to the blood. On the way of lymph flow there are checkpoints - lymph nodes, which receive blood vessels from various places in the human body.

Everyone who has ever visited a therapist knows about the presence of these organs. Lymph nodes are of great importance for the normal functioning of the whole organism. In essence, they are biological filters that do not allow harmful agents to penetrate organs and tissues. The lymph passing through them is cleared of bacteria and other foreign substances, enriched with antibodies, thereby providing adequate protection for the whole organism.

Lymph nodes work around the clock, without "breaks and days off." Collecting lymph from every corner of the human body, these organs constantly guard our health. Trying to find out if everything is in order with the patient, the doctor first of all palpates the lymph nodes of various localizations. Based on the state of these organs, one can draw conclusions about the functioning of the whole organism, as well as notice the development of many dangerous diseases in time.

Lymphadenopathy: what is it? Reasons for development

Performing the function of a collector, the lymph node is forced to collect all the harmful substances that enter the body. Sooner or later, this well-established mechanism can fail, causing a condition called lymphadenopathy of the lymph nodes. What can cause this pathology? There are several such factors:

  • infectious diseases (flu, stomatitis, rubella, tuberculosis and many others);
  • human immunodeficiency virus (HIV);
  • oncological diseases;
  • mechanical injury;
  • allergic reaction;
  • diseases of the internal organs.

Classification

Depending on the degree of damage to the lymph nodes, the following variants of lymphadenopathy are distinguished:

  • localized (local enlargement of one lymph node);
  • regional (lesion of lymph nodes in two adjacent areas);
  • generalized (changes in lymph nodes in more than three groups)

The localized form occurs in 70% of cases and is usually associated with a limited infectious process or trauma. Lymphadenopathy of the cervical lymph nodes is characterized by their regional lesion, and generalized inflammation indicates a serious violation in the human immune status.

Symptoms

Regardless of localization, this pathology has a number of similar features that make it possible to recognize it among other diseases. Affected lymph nodes are enlarged, hot and painful to the touch. Unpleasant sensations are possible in the area of ​​localization of the process, especially when changing the position of the body.

Common symptoms include fever, weakness, chills. In the acute period, an increase in the liver and spleen is possible. With an infectious lesion, signs of a disease that provoked an increase in lymph nodes come to the fore.

An experienced doctor already at the initial examination will be able to make a diagnosis and determine the tactics of further treatment of the patient. Knowing exactly how the lymph moves through the body, you can find out not only the localization, but also the cause of the pathological process. Let us consider in more detail each particular case of enlarged lymph nodes.

Enlarged cervical lymph nodes

Cervical lymphadenopathy is quite common. Lymphadenitis, localized in this area, is dangerous due to its proximity to the structures of the brain. If the immune system fails to cope with the problem that has arisen, the consequences for a person can be the saddest.

Lymphadenopathy of the cervical lymph nodes can be caused by a variety of reasons. Most often, this condition develops when a viral or bacterial infection (flu or other acute respiratory infections) enters the body. The most typical cervical lymphadenitis for children who have not yet fully formed the immune system. At an early age, even ordinary stomatitis or gingivitis can cause a sharp increase in submandibular lymph nodes, which is accompanied by high fever and chills.

Cervical lymphadenopathy can be associated with various malignant neoplasms, which makes doctors especially attentive to this symptom. In this case, the patient needs to consult not only a therapist, but also an oncologist. With syphilis and tuberculosis, an increase in lymph nodes is also one of the most common symptoms.

Enlarged lymph nodes in the chest area

Mediastinal lymphadenopathy is considered among doctors one of the most dangerous symptoms. In most cases, this condition develops in patients after 40 years of age and indicates the presence of a malignant neoplasm. It can be either a tumor of the lungs or heart, or metastases from the abdominal cavity or small pelvis. In any case, such a pathology requires prompt diagnostics, which includes ultrasound examination of internal organs, magnetic resonance imaging, and biopsy of affected tissues.

Lymphadenopathy of the mediastinum can occur in various diseases of the internal organs. Most often we are talking about the pathology of the thyroid gland, the dysfunction of which leads to a change in the flow of lymph. Some connective tissue diseases (systemic lupus erythematosus, scleroderma, and others) can also become a direct cause of lymphadenitis.

Inflammation of the lung lymph nodes

This situation is a fairly common finding on radiography. Lymphadenopathy of the lungs is a special case of damage to the lymph nodes of the mediastinum. A similar symptom may indicate the development of such a dangerous disease as lung cancer. Usually this pathology occurs in older people who smoke or work in hazardous industries. It is not excluded the development of tuberculosis or sarcoidosis - in both cases, pulmonary lymphadenopathy is one of the very first symptoms. With banal pneumonia and bronchitis, a change in the lymph nodes also occurs. For a more accurate diagnosis, you should take a picture of the affected organ in two projections, and be sure to visit a phthisiatrician or oncologist.

Enlarged axillary lymph nodes

The lymph nodes of this localization are very sensitive to the slightest changes in the immune status and can increase even with the usual flu or SARS. In this case, axillary lymphadenopathy does not require special treatment and goes away by itself when recovering from the underlying disease. With any serious injury to the upper limbs, the lymph nodes of this localization are also involved in the pathological process.

A similar symptom in women of any age deserves close attention. Axillary lymphadenopathy can be one of the first signs of breast cancer. If such abnormalities are found in herself, a woman should immediately sign up for a consultation with a mammologist.

Generalized lymphadenopathy

This term in medicine is called an increase in three or more groups of lymph nodes, lasting more than one month. In children and adolescents, the most common cause of this condition is infectious mononucleosis, a disease caused by the Epstein-Barr virus. In some situations, the symptoms turn out to be smoothed out, and the pathological process proceeds under the guise of a common cold. Occasionally, an increase in a large number of lymph nodes occurs with rubella and measles.

Generalized lymphadenopathy in adults may indicate the development of HIV infection. In this case, the process affects three or more groups of lymph nodes and lasts at least three months. ELISA will help confirm the diagnosis - an analysis for the detection of antibodies of the immunodeficiency virus in peripheral blood.

Diagnostics

During the initial examination, palpation of the affected lymph nodes is performed. The doctor determines the localization of the process, the consistency and soreness of the altered organ. In most cases, such a simple technique allows you to determine the vector of further examination and make a preliminary diagnosis.

After collecting an anamnesis and identifying risk factors, the doctor prescribes laboratory examinations, among which there will necessarily be general blood and urine tests. If necessary, ultrasound of the internal organs, X-ray of the lungs, as well as magnetic resonance imaging are performed. All these manipulations allow you to find out the cause of lymphadenitis and determine the tactics of treatment.

In some cases, it may be necessary to puncture the affected lymph node, followed by a biopsy. This method allows you to accurately find out the reason for the development of lymphadenopathy. What it is? Under local anesthesia, a puncture is made with a thin needle, after which a piece of the desired tissue is taken. This procedure allows you to identify metastases in an enlarged lymph node, detect a purulent process or other pathological changes.

Treatment of lymphadenopathy

It is worth considering the fact that an increase in lymph nodes in itself is not some kind of separate disease. That is why it is so important to find the cause due to which lymphadenopathy developed. Treatment will depend on the underlying diagnosis and the identification of factors that triggered the appearance of such a problem.

In the event that lymphadenitis is caused by any infectious agent, the patient is sent under the supervision of a therapist. For most viral and bacterial diseases, no special treatment is required: after recovery, the lymph nodes will return to their normal state on their own.

Quite often, oncological diseases lead to such a phenomenon as lymphadenopathy. Treatment in this case will depend on the severity of the underlying disease. The treatment regimen is approved by the oncologist and may include both surgery and other available methods.

In some cases, an enlarged lymph node can be caused by direct trauma. In this case, the patient also gets on the table to the surgeon. Opening the affected organ with the removal of purulent contents allows you to completely solve the problem of lymphadenopathy.

Any unreasonable enlargement of the lymph nodes requires a thorough examination by a specialist. Even if lymphadenopathy is not a sign of a serious illness, it can cause some discomfort and lead to a deterioration in overall well-being. Timely diagnosis allows not only to prevent the development of the pathological process, but also to help the patient cope with his own fears regarding the current situation.

Lymph nodes are essential part of the immune system.

Their inflammation may indicate a disease of any organ or organism as a whole.

In this case, you need to seek help from a specialist, since axillary lymphadenopathy may be only the first sign of any disease.

What is lymphadenopathy?

Lymphadenopathy is a condition in which the size of the lymphatic vessels of various origins increase.

In 75% of cases, with such a disease, inflammation only one lymph node is exposed.

Most often, lymphadenopathy occurs in the axillary or .

Sometimes the usual inflammation of the lymph nodes is confused with a disease called lymphadenitis. They are similar but have one difference. With lymphadenitis, in places of enlargement of the lymphatic vessels, accumulations of pus form, which is more dangerous for human health.

Features of the disease in the armpit

There are several forms of the disease depending on the severity:

  1. Localized(inflammation occurs only in one lymph node);
  2. Regional(several lymphatic vessels increase in one or two adjacent zones);
  3. Generalized(affected by three or more nodes in several different areas).

The localized form is the most common(more than 70% of the population). Generalized lymphadenopathy is considered the most dangerous type.

Also varies acute and chronic form of the disease. In the acute form, the sites of inflammation of the lymph nodes are accompanied by pain, swelling and fever. Chronic lymphadenopathy is asymptomatic for a long time.

Inflammation of the lymphatic system is the first sign of a serious illness. Thus, a unilateral (right or left) enlargement of the lymph nodes may indicate diseases such as:

  • breast carcinoma;
  • Leaf;
  • Brucellosis.

The appearance of so-called "bumps" in the armpit on the left and right at the same time (bilateral lymphadenopathy) says about the presence of venereal diseases.

The reasons

Other causes of lymphadenopathy in the armpit are:

Symptoms

The main signs of lymphadenopathy include:

Diagnostics

In order to make an accurate diagnosis and prescribe an effective course of treatment, you will need determine the cause of inflammation of the lymph node. Since lymphadenopathy can be just a symptom of another serious disease.

Usually, the following series of standard studies is carried out for diagnosis:

  • UAC and OAM;
  • Ultrasound examination of the abdominal cavity;
  • tumor markers;
  • radiography;
  • Blood chemistry;
  • Serological tests for EBV, CMV, toxoplasmosis and HIV;
  • Taking a sample for tuberculosis.

Sometimes an additional lymph node biopsy.

look ultrasound procedure video with lymphadenopathy of the axillary region:

Differences between adult and childhood illness

At present, the disease children under the age of 12 are more susceptible. This is because the lymphatic system is considered immature. Although the development of lymph nodes begins when the child is still in the womb.

The first year of a child's life is considered critical. since a rapid increase in lymph nodes begins, which are difficult to palpate.

In adulthood, lymphadenopathy is easier to detect than in adolescence or at birth.

The difference is only detection difficulty, everything else depends on the location, severity and cause.

Treatment

The method of treatment is determined after receiving the results of examinations, questioning the patient and making a diagnosis.

Treatment depends only on the identified cause of the disease:

  • If this is the reason infectious nature, then a course of drugs aimed at combating the virus (for example, Acyclovir; Rimantadine) or antibacterial drugs (Amoxiclav; Ceftriaxone; Clindamycin) is prescribed.
  • If the cause of inflammation of the lymph nodes is oncological diseases, then a course of radio- and chemotherapy is prescribed.

Also conduct a course of physiotherapy:

Sometimes treatment of lymphadenopathy requires surgical intervention.

Some people prefer folk medicine, in which for recovery use:

  1. Herbal decoctions;
  2. echinacea tincture;
  3. Warming of the lymph nodes.

Attention! Warming is strictly prohibited during the development of adenophlegmon, the presence of tuberculosis and a tumor in an enlarged lymph node or signs of intoxication of the body (fever, headaches).

Alternative methods of treatment can be used only after the final diagnosis, in therapy with antibacterial drugs and with the permission of the doctor.

Prevention

To prevent the onset of disease several rules must be followed:

Axillary lymphadenopathy is inflammation in the lymph nodes. In most cases, swollen lymph nodes are just a symptom of a more serious disease. Timely treatment, as well as preventive measures, will help maintain health.